2-(2-氯嘧啶-4-基氨基)乙醇合成路线 （共 2 条）
反应条件
N-ethyl-N,N-diisopropylamine in ethanol
T=50°C; 12 h;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH; THE SCRIPPS RESEARCH INSTITUTE
Patent: WO2005/68437 A1, 2005 ;
Location in patent: Page/Page column 30 ;
反应条件
boron tribromide in dichloromethane
T=-10 - 20°C; 3 h;
参考文献
Biota Europe Ltd.; Lunniss, Christopher James; Palmer, James T.; Pitt, Gary Robert William; Davies, David; Axford, Lorraine Claire
Patent: US2013/252938 A1, 2013 ;
Location in patent: Paragraph 0521 ;
