氰化锌合成路线 - 魔法化学

参考文献

Patrick, Timothy B.; Juehne, Thomas; Reeb, Elmer; Hennessy, Daniel
Tetrahedron Letters, 2001 , vol. 42, # 21 p. 3553 - 3554

53857-57-15-溴吲唑+

557-21-1氰化锌

74626-47-4吲唑-5-甲腈

参考文献

MERCK SERONO S.A.
Patent: WO2009/80663 A1, 2009 ;
Location in patent: Page/Page column 113 ;
WO 2009/080663 A1

557-21-1氰化锌+

53857-57-15-溴吲唑

74626-47-4吲唑-5-甲腈

参考文献

MERCK SERONO S.A.; QUATTROPANI, Anna; BAKER-GLENN, Charles; BLACKABY, Wesley; KNIGHT, Chris
Patent: WO2010/142628 A1, 2010 ;
Location in patent: Page/Page column 82 ;
WO 2010/142628 A1

150-19-63-甲氧基苯酚+

557-21-1氰化锌

673-22-32-羟基-4-甲氧基苯甲醛

参考文献

Rao, K. V. B.; Iyer, R. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 11 p. 992 - 995

28489-45-42-羟基-5-硝基-6-甲基吡啶+

557-21-1氰化锌

65169-58-66-氰基-2-甲基-3-硝基吡啶

参考文献

Melton, Laura J.
Patent: US2005/281746 A1, 2005 ;
Location in patent: Page/Page column 15-16 ;

22282-96-82-溴-5-硝基-6-甲基吡啶+

557-21-1氰化锌

65169-58-66-氰基-2-甲基-3-硝基吡啶

参考文献

Sanderson, Philip E. J.; Stanton, Matthew G.; Dorsey, Bruce D.; Lyle, Terry A.; McDonough, Colleen; Sanders, William M.; Savage, Kelly L.; Naylor-Olsen, Adel M.; Krueger, Julie A.; Lewis, S. Dale; Lucas, Bobby J.; Lynch, Joseph J.; Yan, Youwei
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 5 p. 795 - 798

557-21-1氰化锌+

15115-60-34-溴-1-茚酮

60899-34-52,3-二氢-1-氧代-1H-茚-4-甲腈

参考文献

RECEPTOS, INC.; MARTINBOROUGH, Esther; BOEHM, Marcus, F.; YEAGER, Adam, Richard; TAMIYA, Junko; HUANG, Liming; BRAHMACHARY, Enugurthi; MOORJANI, Manisha
Patent: WO2011/60389 A1, 2011 ;
Location in patent: Page/Page column 87-88 ;
WO 2011/060389 A1

500-99-23,5-二甲氧基苯酚+

557-21-1氰化锌

708-76-94,6-二甲氧基水杨醛

参考文献

Verhe; De Kimpe; De Buyck; et al.
Bulletin des Societes Chimiques Belges, 1980 , vol. 89, # 6 p. 459 - 485

7025-06-12-溴联苯醚+

557-21-1氰化锌

6476-32-02-苯氧基苯腈

参考文献

ASTRAZENECA AB
Patent: US2008/15237 A1, 2008 ;
Location in patent: Page/Page column 34 ;
US 20080015237 A1

557-21-1氰化锌+

612-61-37-氯喹啉

67360-38-77-喹啉甲腈

参考文献

Hirner, Joshua J.; Zacuto, Michael J.
Tetrahedron Letters, 2009 , vol. 50, # 35 p. 4989 - 4993