氰化锌合成路线 - 魔法化学

参考文献

Alantos Pharmaceuticals Holding, Inc.
Patent: US2008/21024 A1, 2008 ;
Location in patent: Page/Page column 79 ;
US 20080021024 A1

557-21-1氰化锌+

27007-53-02-溴-5-氯苯甲酸甲酯

439117-38-15-氯-2-氰基苯甲酸甲酯

参考文献

MERCK SHARP and DOHME CORP.; XU, Libo; CHOBANIAN, Harry; CAMPBELL, Brian, T.; GUO, Yan; PIO, Barbara; ZHANG, Rui
Patent: WO2014/25658 A1, 2014 ;
Location in patent: Page/Page column 25 ;

557-21-1氰化锌+

494210-98-9

439117-38-15-氯-2-氰基苯甲酸甲酯

参考文献

Frantz, Doug E.; Weaver, Damian G.; Carey, James P.; Kress, Michael H.; Dolling, Ulf H.
Organic Letters, 2002 , vol. 4, # 26 p. 4717 - 4718

27007-53-02-溴-5-氯苯甲酸甲酯+

557-21-1氰化锌

439117-38-15-氯-2-氰基苯甲酸甲酯

参考文献

Morrissette, Matthew M.; Stauffer, Kenneth J.; Williams, Peter D.; Lyle, Terry A.; Vacca, Joseph P.; Krueger, Julie A.; Lewis, S. Dale; Lucas, Bobby J.; Wong, Bradley K.; White, Rebecca B.; Miller-Stein, Cynthia; Lyle, Elizabeth A.; Wallace, Audrey A.; Leonard, Yvonne M.; Welsh, Denise C.; Lynch, Joseph J.; McMasters, Daniel R.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 16 p. 4161 - 4164

557-21-1氰化锌+

494210-98-9

439117-38-15-氯-2-氰基苯甲酸甲酯

参考文献

Nelson, Todd D.; LeBlond, Carl R.; Frantz, Doug E.; Matty, Louis; Mitten, Jeffrey V.; Weaver, Damian G.; Moore, Jeffrey C.; Kim, Jaehon M.; Boyd, Russell; Kim, Pei-Yi; Gbewonyo, Kodzo; Brower, Mark; Sturr, Michael; McLaughlin, Kathleen; McMasters, Daniel R.; Kress, Michael H.; McNamara, James M.; Dolling, Ulf H.
Journal of Organic Chemistry, 2004 , vol. 69, # 11 p. 3620 - 3627

557-21-1氰化锌+

325142-95-82,6-二甲基吡啶-4-硼酸频那醇酯

39965-81-62,6-二甲基-4-氰基吡啶

参考文献

Liskey, Carl W.; Liao, Xuebin; Hartwig, John F.
Journal of the American Chemical Society, 2010 , vol. 132, # 33 p. 11389 - 11391

557-21-1氰化锌+

108530-08-18-喹啉三氟甲烷磺酸

35509-27-48-喹啉甲腈

参考文献

Journal of Medicinal Chemistry, , vol. 52, # 3 p. 868 - 877

33863-76-21-溴-3-氯-5-氟苯+

557-21-1氰化锌

327056-73-53-氯-5-氟苯腈

参考文献

PFIZER LIMITED
Patent: WO2006/67587 A2, 2006 ;
Location in patent: Page/Page column 32; 33 ;

557-21-1氰化锌+

701285-81-6

52805-36-44-苯甲氧基苯甲腈

参考文献

Srivastava, Rajiv R.; Zych, Andrew J.; Jenkins, David M.; Wang, Hong-Jun; Chen, Zhen-Jia; Fairfax, David J.
Synthetic Communications, 2007 , vol. 37, # 3 p. 431 - 438

60710-80-73-氨基-4-甲基苯甲腈

参考文献

Journal of Medicinal Chemistry, , vol. 47, # 3 p. 612 - 626