4-溴甲基-3-硝基苯甲酸合成路线 （共 17 条）
反应条件
nitric acid T=0°C; 1 h;
参考文献
Barany, George; Albericio, Fernando
Journal of the American Chemical Society, 1985 , vol. 107, # 17 p. 4936 - 4942
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in benzene 36 h; Heating;
参考文献
Pillai, V. N. Rajasekharan; Mutter, Manfred; Bayer, Ernst; Gatfield, Ian
Journal of Organic Chemistry, 1980 , vol. 45, # 26 p. 5364 - 5370
反应条件
in HNO3 (white fumming)
反应条件
1: 72 percent / benzoyl peroxide, N-bromosuccinimide / 1.5 h / Heating 2: 89 percent / fuming HNO3 / 1 h / 0 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 107, # 17 p. 4936 - 4942
反应条件
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane T=0°C; 0.333333 h;
参考文献
Lopes, Marcela S.; De Souza Pietra, Renata C.C.; Borgati, Tatiane F.; Romeiro, Carla F.D.; Junior, Policarpo A.S.; Romanha, Alvaro J.; Alves, Ricardo J.; Souza-Fagundes, Elaine M.; Fernandes, Ana Paula S.M.; De Oliveira, Renata B.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 11 p. 5443 - 5447
反应条件
ammonia in ethanol T=-78 - 25°C;
参考文献
Lee, Hong Boon; Zaccaro, Maria Clara; Pattarawarapan, Mookda; Roy, Sudipta; Saragovi, H. Uri; Burgess, Kevin
Journal of Organic Chemistry, 2004 , vol. 69, # 3 p. 701 - 713
反应条件
in ethanol; ammonia; water
参考文献
Cappelletti, Enrico; Lattuada, Luciano; Linder, Karen E.; Marinelli, Ed; Nanjappan, Palaniappa; Raju, Natarajan; Swenson, Rolf E.; Tweedle, Michael
Patent: US2004/136906 A1, 2004 ;
反应条件
1: 29 percent / KI, H2O / 18 h / Heating 2: 58 percent / N,N'-dicyclohexylcarbodiimide / CH2Cl2 / 18 h View Scheme
参考文献
Lloyd-Williams, Paul; Gairi, Margarida; Albericio, Fernando; Giralt, Ernest
Tetrahedron, 1991 , vol. 47, # 47 p. 9867 - 9880
反应条件
thionyl chloride
6 h; Heating;
参考文献
Younes, M.E.; Rahman, S. Abdel; Hattaba, A.
Collection of Czechoslovak Chemical Communications, 1987 , vol. 52, # 5 p. 1352 - 1355
反应条件
sodium carbonate in acetone
5 h; Heating;
参考文献
Eisenfuehr, Alexander; Arora, Paramjit S; Sengle, Gerhard; Takaoka, Leo R; Nowick, James S; Famulok, Michael
Bioorganic and medicinal chemistry, 2003 , vol. 11, # 2 p. 235 - 249
