8-甲氧基-1,7-萘啶-6-胺合成路线 （共 3 条）
反应条件
1: 46 percent / aq. NaNO2 / 3 h / 0 °C 2: 75 percent / Pd(dba)2; PPh3; 2 N aq. Na2CO3 / dimethylformamide / 2 h / 80 °C 3: 73 percent / PBr3 / dimethylformamide / 0.5 h / 100 °C View Scheme
参考文献
Hersperger, Rene; Dawson, Janet; Mueller, Thomas
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 2 p. 233 - 235
反应条件
sodium
T=20°C; 16 h;
参考文献
Hersperger, Rene; Dawson, Janet; Mueller, Thomas
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 2 p. 233 - 235
反应条件
1: 46 percent / aq. NaNO2 / 3 h / 0 °C
2: 75 percent / Pd(dba)2; PPh3; 2 N aq. Na2CO3 / dimethylformamide / 2 h / 80 °C
3: 73 percent / PBr3 / dimethylformamide / 0.5 h / 100 °C
4: Pd(dba)2; P(o-tol)3; 2 N aq. Na2CO3 / dimethylformamide / 2 h / 110 °C
View Scheme
参考文献
Hersperger, Rene; Dawson, Janet; Mueller, Thomas
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 2 p. 233 - 235
