1.1: potassium carbonate / N,N-dimethyl-formamide / 13 h / 20 °C / Cooling with ice
2.1: n-butyllithium / toluene; hexane / 0.95 h / -78 °C
2.2: 1 h / -78 °C
2.3: 2 h / -10 - 20 °C
View Scheme
参考文献
JAPAN TOBACCO INC.
Patent: US2011/77267 A1, 2011 ;
US 20110077267 A1