N-甲氧基羰基顺丁烯二酰亚胺合成路线 （共 23 条）
反应条件
sodium hydrogencarbonate in water T=0 - 20°C;
参考文献
Foley, Timothy L.; Yasgar, Adam; Garcia, Christopher J.; Jadhav, Ajit; Simeonov, Anton; Burkart, Michael D.
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 20 p. 4601 - 4606
参考文献
Centocor
Patent: US5180816 A1, 1993 ;
反应条件
sodium hydrogencarbonate T=0 - 23°C; 1 h;
参考文献
Heredia, Karina L.; Bontempo, Debora; Ly, Tiffany; Byers, Joshua T.; Halstenberg, Sven; Maynard, Heather D.
Journal of the American Chemical Society, 2005 , vol. 127, # 48 p. 16955 - 16960
反应条件
sodium hydrogencarbonate
参考文献
Sun, Chengzao; Aspland, Simon E.; Ballatore, Carlo; Castillo, Rosario; Smith III, Amos B.; Castellino, Angelo J.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 1 p. 104 - 107
反应条件
sodium hydrogencarbonate in water T=0 - 25°C;
参考文献
Constant, Celine; Albert, Steeve; Zivic, Nicolas; Baczko, Krystyna; Fensterbank, Helene; Allard, Emmanuel
Tetrahedron, 2014 , vol. 70, # 18 p. 3023 - 3029
反应条件
sodium hydrogencarbonate in tetrahydrofuran 4 h; Ambient temperature; Yield given;
参考文献
Cheronis, John C.; Whalley, Eric T.; Allen, Lisa G.; Loy, Sharon D.; Elder, Megan W.; et al.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 3 p. 348 - 355
反应条件
sodium hydrogencarbonate T=0 - 25°C;
参考文献
Keller, Keith A.; Guo, Jianhua; Punna, Sreenivas; Finn
Tetrahedron Letters, 2005 , vol. 46, # 7 p. 1181 - 1184
反应条件
1: mPEG (20 kDa)-amine in dichloromethane T=40°C; 2: With sodium carbonate; sodium sulfate in dichloromethane T=5 - 5.75°C; 9.5 - 15 h; 3: N-methoxycarbonyl-maleimide in dichloromethane T=5 - 40°C; 29 - 30.75 h; Heating / reflux; Product distribution / selectivity;
参考文献
Kozlowski, Antoni; Handley, John; Schaefer, Anthony G.; Bray, Brian; Odom, Ryan; Sander, Tony L.
Patent: US2007/49688 A1, 2007 ;
Location in patent: Page/Page column 15-17 ;
参考文献
Weissler, Manfred; Kliem, Hans-Christian; Sauerbrei, Bernd; Schmauser, Birgit
Patent: US2004/59101 A1, 2004 ;
反应条件
sodium hydrogencarbonate in tetrahydrofuran
3 h; Ambient temperature;
参考文献
Cheronis, John C.; Whalley, Eric T.; Nguyen, Khe T.; Eubanks, Shad R.; Allen, Lisa G.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 9 p. 1563 - 1572
