2,5-二氧代吡咯-1-甲酸乙酯合成路线 （共 4 条）
反应条件
4-(N,N-dimethlyamino)pyridine in ethyl acetate T=5 - 20°C;
参考文献
El-Mahdy, Ahmed F. M.; Shibata, Takayuki; Kabashima, Tsutomu; Kai, Masaaki
Chemical Communications, 2014 , vol. 50, # 7 p. 859 - 861
反应条件
in tetrahydrofuran; sodium hydrogencarbonate
参考文献
Boehringer Mannheim GmbH
Patent: US5595741 A1, 1997 ;
反应条件
sodium hydrogencarbonate in water T=0 - 20°C; 1.5 h;
参考文献
YUAN, Ta Tung; CHUANG, Shih-Hsien; LIU, Tzu-Yin
Patent: WO2011/9047 A2, 2011 ;
Location in patent: Page/Page column 16-17 ;
反应条件
sodium hydrogencarbonate in water
参考文献
Raouane, Mouna; Desmaele, Didier; Gilbert-Sirieix, Marie; Gueutin, Claire; Zouhiri, Fatima; Bourgaux, Claudie; Lepeltier, Elise; Gref, Ruxandra; Ben Salah, Ridha; Clayman, Gary; Massaad-Massade, Liliane; Couvreur, Patrick
Journal of Medicinal Chemistry, 2011 , vol. 54, # 12 p. 4067 - 4076
