反应条件
1: 88 percent / N,N-dimethylaniline, POCl3 / 1,2-dichloro-ethane / 18 h / Heating
2: 70 percent / tetrahydrofuran; methanol / 18 h / Ambient temperature
View Scheme
参考文献
Capps, David B.; Dunbar, James; Kesten, Suzanne R.; Shillis, Joan; Werbel, Leslie M.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 26 p. 4770 - 4778
