3-氨基-5-叔丁基异唑合成路线 （共 28 条）
反应条件
hydrogenchloride; sodium hydroxide; hydroxylammonium sulfate; triethylamine in methanol; toluene
参考文献
Shionogi and Co., Ltd.
Patent: US4200757 A1, 1980 ;
反应条件
hydrogenchloride; sodium hydroxide; hydroxylammonium sulfate in water
参考文献
Shionogi and Co., Ltd.
Patent: US4256899 A1, 1981 ;
反应条件
lithium hydroxide; hydroxylamine hydrochloride in ethanol; water
参考文献
Eli Lilly and Company
Patent: US4259501 A1, 1981 ;
反应条件
hydrogenchloride in methanol T=50°C; 3 h;
参考文献
Takase, Akira; Murabayashi, Akira; Sumimoto, Shinzaburo; Ueda, Shiro; Makisumi, Yasuo
Heterocycles, 1991 , vol. 32, # 6 p. 1153 - 1158
反应条件
sodium hydroxide; hydroxylamine hydrochloride in ethanol; water
反应条件
hydrogenchloride 16 h; Heating;
参考文献
Heterocycles, , vol. 32, # 6 p. 1153 - 1158
反应条件
sodium hydroxide; water in chloroform; N,N-dimethyl-formamide T=144 - 145°C; 1 h; Product distribution;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 32, # 7 p. 2736 - 2744
反应条件
hydrogenchloride; water in N,N-dimethyl-formamide T=100°C; 0.666667 h; other temperatures; Product distribution;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 32, # 7 p. 2841 - 2844
反应条件
water in chloroform; N,N-dimethyl-formamide T=157 - 163°C; 0.0166667 h; Product distribution;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 32, # 7 p. 2841 - 2844
反应条件
hydrogenchloride; sodium hydroxide; hydroxylammonium sulphate 1.) pH 8.20, 100 deg C, 30 min, 2.) 100 deg C, 15 min; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Heterocycles, , vol. 32, # 6 p. 1153 - 1158
