反应条件
1: 1) n-BuLi / 1) THF, -78 deg C, 1 min, 2) THF, -78 deg C, 15 min
2: 84 percent / pyridinium chlorochromate, 4 Angstroem molecular sieves, Celite / CH2Cl2 / 1) 0 deg C -> room temperature, 2) room temperature, 29 h
3: 92 percent / HCl, air / H2O / 2 h / Heating
4: 1) t-BuOK / 1) DME, THF, room temperature, 30 min, 2) DME, THF, reflux, 4 d
5: 57 percent / CH3COOK, Bu4NBr, Pd(CH3COO)2 / acetonitrile / 3 h / Heating
View Scheme
参考文献
Comins, Daniel L.; Saha, Jayanta K.
Journal of Organic Chemistry, 1996 , vol. 61, # 26 p. 9623 - 9624
