(2-氨基-3-噻吩)(4-氯苯基)甲酮合成路线 （共 5 条）
反应条件
1: in ethanol
T=20°C; 0.166667 h;
2: With N-methylpiperazine-functionalized Polyacrylonitrile Fiber in ethanol
Gewald Aminoheterocycles Synthesis; 5 h; Reflux;
参考文献
Ma, Lichao; Yuan, Liwei; Xu, Changzhu; Li, Guowei; Tao, Minli; Zhang, Wenqin
Synthesis (Germany), 2013 , vol. 45, # 1 art. no. SS-2012-H0716-OP, p. 45 - 52
反应条件
morpholine; sulfur in ethanol
T=70°C; Cyclization; 1 h;
参考文献
Baraldi, Pier Giovanni; Zaid, Abdel Naser; Lampronti, Ilaria; Fruttarolo, Francesca; Pavani, Maria Giovanna; Tabrizi, Mojgan Aghazadhe; Shryock, John C.; Leung, Edward; Romagnoli, Romeo
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 17 p. 1953 - 1957
反应条件
1: ethanol; H2O / 2 h / 20 °C
2: 45 percent / sulfur; morpholine / ethanol / 1 h / 70 °C
View Scheme
参考文献
Baraldi, Pier Giovanni; Zaid, Abdel Naser; Lampronti, Ilaria; Fruttarolo, Francesca; Pavani, Maria Giovanna; Tabrizi, Mojgan Aghazadhe; Shryock, John C.; Leung, Edward; Romagnoli, Romeo
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 17 p. 1953 - 1957
反应条件
1.1: sulfuric acid / 5 h / |Reflux
2.1: sodium methylate / 6 h / |Reflux; |Inert atmosphere
3.1: ethanol / 0.17 h / 20 °C
3.2: N-methylpiperazine-functionalized Polyacrylonitrile Fiber / 5 h / |Reflux
View Scheme
参考文献
Ma, Lichao; Yuan, Liwei; Xu, Changzhu; Li, Guowei; Tao, Minli; Zhang, Wenqin
Synthesis (Germany), 2013 , vol. 45, # 1 art. no. SS-2012-H0716-OP, p. 45 - 52
反应条件
1.1: sodium methylate / 6 h / |Reflux; |Inert atmosphere
2.1: ethanol / 0.17 h / 20 °C
2.2: N-methylpiperazine-functionalized Polyacrylonitrile Fiber / 5 h / |Reflux
View Scheme
参考文献
Ma, Lichao; Yuan, Liwei; Xu, Changzhu; Li, Guowei; Tao, Minli; Zhang, Wenqin
Synthesis (Germany), 2013 , vol. 45, # 1 art. no. SS-2012-H0716-OP, p. 45 - 52
