2-苯甲酰-2-溴乙酸乙酯合成路线 （共 24 条）
反应条件
1: 2) aq. NaHCO3 / 1) acetone, reflux, 2) CH2Cl2, 20 deg C
2: 1) KOH, 2) aq. HCl / 1) EtOH, H2O, 2 h, reflux, 2) 2 h, reflux
View Scheme
参考文献
Compton, Victoria J.; Meakins, G. Denis; Raybould, Amanda J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 15 p. 2029 - 2032
反应条件
in ethanol
8 h; Heating;
参考文献
Abignente; De Caprariis; Rimoli; Capasso; Autore
Farmaco, 1992 , vol. 47, # 6 p. 919 - 930
反应条件
T=55°C; 0.333333 h; neat (no solvent);
参考文献
Chunavala, Kaushik C.; Joshi, Girdhar; Suresh, Eringathodi; Adimurthy, Subbarayappa
Synthesis, 2011 , # 4 art. no. Z27510SS, p. 635 - 641
反应条件
1: diethyl ether; K2CO3
2: ethanolic KOH
View Scheme
参考文献
CIBA
Patent: DE658353 , 1936 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 24, p. 368
