2,3-二氢-1-氧代-1H-茚-4-羧酸甲酯合成路线 （共 4 条）
反应条件
triethylamine; bis-triphenylphosphine-palladium(II) chloride
P=18751.9 Torr; 48 h;
参考文献
MERCK SHARP and DOHME CORP.; ROMEO, Eric Thomas; MACHACEK, Michelle, R.; TROTTER, Benjamin Wesley; MILLER, Thomas Allen; ANDRESEN, Brian Michael; ANTHONY, Neville John; TAOKA, Brandon, M.; LIU, Yuan
Patent: WO2012/151137 A1, 2012 ;
Location in patent: Page/Page column 54 ;
WO 2012/151137 A1
反应条件
1: diethyl ether
2: CrO3, AcOH
View Scheme
参考文献
Pelliciari, Roberto; Luneia, Roberto; Costantino, Gabriele; Marinozzi, Maura; Natalini, Benedetto; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 19 p. 3717 - 3719
反应条件
in diethyl ether
T=0°C;
参考文献
Kirchner, James J.; Pratt, Daniel V.; Hopkins, Paul B.
Tetrahedron Letters, 1988 , vol. 29, # 34 p. 4229 - 4232
反应条件
chromium(VI) oxide; acetic acid
Yield given;
参考文献
Pelliciari, Roberto; Luneia, Roberto; Costantino, Gabriele; Marinozzi, Maura; Natalini, Benedetto; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 19 p. 3717 - 3719
