2,4-二氯-7-甲氧基喹啉合成路线 （共 9 条）
反应条件
1: With trichlorophosphate T=115°C; 3 h; 2: With sodium hydroxide in water T=0°C; pH=10;
参考文献
VIROBAY, INC.
Patent: WO2007/5838 A2, 2007 ;
Location in patent: Page/Page column 71-72 ;
反应条件
trichlorophosphate Heating;
参考文献
Arul Prakash; Rajendran
Heterocyclic Communications, 2001 , vol. 7, # 4 p. 353 - 358
反应条件
in ethyl acetate; trichlorophosphate
参考文献
Bristol-Myers Squibb Company; Hiebert, Sheldon; Rajamani, Ramkumar; Sun, Li-Qiang; Mull, Eric; Gillis, Eric P.; Bowsher, Michael S.; Zhao, Qian; Meanwell, Nicholas A.; Renduchintala, Kishore V.; Sarkunam, Kandhasamy; Nagalakshmi, Pulicharla; Babu, P. V. K. Suresh; Scola, Paul Michael
Patent: US2013/115190 A1, 2013 ;
Location in patent: Page/Page column ;
参考文献
Journal of the Chemical Society, , p. 614,619
反应条件
1: POCl3 2: sodium nitrite; concentrated sulfuric acid 3: phosphoryl chloride View Scheme
参考文献
Journal of the Chemical Society, , p. 614,619
反应条件
1: sodium nitrite; concentrated sulfuric acid 2: phosphoryl chloride View Scheme
参考文献
Journal of the Chemical Society, , p. 614,619
反应条件
trichlorophosphate 3 h; Heating;
参考文献
Osborne, Alan G.; Buley, Jill M.; Clarke, Helen; Dakin, Rachel C. H.; Price, Paul I.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 22 p. 2747 - 2756
参考文献
VIROBAY, INC.
Patent: WO2007/5838 A2, 2007 ;
Location in patent: Page/Page column 72 ;
反应条件
[3,2-c]pyrazole in ethyl acetate
参考文献
Bristol-Myers Squibb Company; Hiebert, Sheldon; Rajamani, Ramkumar; Sun, Li-Qiang; Mull, Eric; Gillis, Eric P.; Bowsher, Michael S.; Zhao, Qian; Meanwell, Nicholas A.; Renduchintala, Kishore V.; Sarkunam, Kandhasamy; Nagalakshmi, Pulicharla; Babu, P. V. K. Suresh; Scola, Paul Michael
Patent: US2013/115190 A1, 2013 ;
Location in patent: Page/Page column ;
