1-(2-溴乙基)吡咯烷-2,5-二酮合成路线 （共 6 条）
反应条件
1: pyrrolidin-1-yl-2,5-dione With potassium tert-butylate; tetrabutylammomium bromide in dichloromethane 2: ethylene dibromide in dichloromethane 5 h; Heating;
参考文献
Lion, Claude; Da Conceicao, Louis; Hedayatullah, Mir
Phosphorus, Sulfur and Silicon and Related Elements, 2000 , vol. 161, p. 97 - 113
反应条件
potassium carbonate in ethanol; water
反应条件
1: pyrrolidin-1-yl-2,5-dione With potassium carbonate; potassium iodide 1 h; Reflux; 2: 1-bromo-2-chloro-ethane
参考文献
WO2013/1498 A1, ;
Page/Page column 31; 32 ;
WO 2013/001498 A1
参考文献
Chemische Berichte, , vol. 40, p. 4406
反应条件
1: 20 percent / K2CO3 / ethanol / 4 h / Heating 2: pyridine / 16.5 h 3: methanol / Heating View Scheme
参考文献
Nochi; Shimomura; Hattori; Sato; Miyake; Tanizawa
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 10 p. 2855 - 2857
反应条件
1: 20 percent / K2CO3 / ethanol / 4 h / Heating 2: pyridine / 16.5 h View Scheme
参考文献
Nochi; Shimomura; Hattori; Sato; Miyake; Tanizawa
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 10 p. 2855 - 2857
