3-溴-4-苯基-2-丁酮合成路线 （共 9 条）
反应条件
Oxonereg;; NH4Br in methanol
0.5 h; Reflux; regioselective reaction;
参考文献
MacHarla, Arun Kumar; Chozhiyath Nappunni, Rohitha; Marri, Mahender Reddy; Peraka, Swamy; Nama, Narender
Tetrahedron Letters, 2012 , vol. 53, # 2 p. 191 - 195
反应条件
(Ph)3P+CH2CH2COOH*Br3- in tetrahydrofuran
2 h; Ambient temperature;
参考文献
Besse; Renard; Veschambre
Tetrahedron Asymmetry, 1994 , vol. 5, # 7 p. 1249 - 1268
反应条件
water in ethanol
T=30°C; 120 h; Reagent/catalyst;
参考文献
Zampieri, Davila S.; De Paula, Bruno R.S.; Zampieri, Luiz A.; Vale, Juliana A.; Rodrigues, J. Augusto R.; Moran, Paulo J.S.
Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 85-86, p. 61 - 64
反应条件
aluminum oxide; sodium carbonate; copper(ll) bromide in benzene
T=50°C; 1 h;
参考文献
Aoyama, Tadashi; Takido, Toshio; Kodomari, Mitsuo
Tetrahedron Letters, 2004 , vol. 45, # 9 p. 1873 - 1876
反应条件
water; 1-n-butyl-3-methylimidazolium hexafluorophosphate
T=30°C; 24 h; Reagent/catalyst;
参考文献
Zampieri, Davila S.; De Paula, Bruno R.S.; Zampieri, Luiz A.; Vale, Juliana A.; Rodrigues, J. Augusto R.; Moran, Paulo J.S.
Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 85-86, p. 61 - 64
反应条件
1: aniline With hydrogen bromide; sodium nitrite in water
T=-5 - 5°C;
2: methyl vinyl ketone With copper(ll) bromide in water; acetone
T=20 - 25°C; Meerwein arylation;
参考文献
Ostapiuk; Matiichuk; Pidlypnyi; Obushak
Russian Journal of Organic Chemistry, 2012 , vol. 48, # 4 p. 519 - 522
反应条件
Pichia stipitis cells in ethanol; water
T=30°C; Enzymatic reaction;
参考文献
Zampieri, Davila S.; Zampieri, Luiz A.; Rodrigues, J. Augusto R.; De Paula, Bruno R.S.; Moran, Paulo J.S.
Journal of Molecular Catalysis B: Enzymatic, 2011 , vol. 72, # 3-4 p. 289 - 293
反应条件
1: Oxonereg;; sodium bromide / dichloromethane; water / 4 h
2: Pichia stipitis cells / ethanol; water / 30 °C / Enzymatic reaction
View Scheme
参考文献
Zampieri, Davila S.; Zampieri, Luiz A.; Rodrigues, J. Augusto R.; De Paula, Bruno R.S.; Moran, Paulo J.S.
Journal of Molecular Catalysis B: Enzymatic, 2011 , vol. 72, # 3-4 p. 289 - 293
反应条件
N-bromosuccinmide; Schwartz's reagent; copper(I) bromide dimethylsulfide complex
1.) CH2Cl2, r.t.; 2.) CH2Cl2, r.t., 30 min; Yield given. Multistep reaction;
参考文献
Zheng, Bin; Srebnik, Morris
Tetrahedron Letters, 1995 , vol. 36, # 32 p. 5665 - 5668
