3,6-二甲基-9H-咔唑合成路线 （共 23 条）
反应条件
18-crown-6 ether; copper; potassium carbonate in 1,2-dichloro-benzene Ullmann condensation; 24 h; RefluxInert atmosphere;
参考文献
Schroegel, Pamela; Tomkeviciene, Ausra; Strohriegl, Peter; Hoffmann, Sebastian T.; Koehler, Anna; Lennartz, Christian
Journal of Materials Chemistry, 2011 , vol. 21, # 7 p. 2266 - 2273
反应条件
1: With magnesium sulphate heptahydrate in methanol; dichloromethane
2: With sodium tetrahydroborate; palladium 10 on activated carbon
T=100°C; P=1551.49 - 2585.81 Torr; 0.0833333 h; Microwave irradiation;
参考文献
Chakraborty, Suchandra; Chattopadhyay, Gautam; Saha, Chandan
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 1 p. 91 - 98
反应条件
1: 3,6-dibromo-9H-carbazole With n-butyllithium in diethyl ether; hexane
T=0°C; 1 h;
2: With chloro-trimethyl-silane in diethyl ether; hexane
T=23°C; 1 h;
3: methyl iodide Further stages;
参考文献
Cheng, Chen; Kim, Bong Gon; Guironnet, Damien; Brookhart, Maurice; Guan, Changjian; Wang, David Y.; Krogh-Jespersen, Karsten; Goldman, Alan S.
Journal of the American Chemical Society, 2014 , vol. 136, # 18 p. 6672 - 6683
反应条件
palladium 10 on activated carbon in 1,2,4-trimethyl benzene
6 h; Reflux;
参考文献
Schroegel, Pamela; Tomkeviciene, Ausra; Strohriegl, Peter; Hoffmann, Sebastian T.; Koehler, Anna; Lennartz, Christian
Journal of Materials Chemistry, 2011 , vol. 21, # 7 p. 2266 - 2273
反应条件
Au(Ph3P)+NTf2- in toluene
T=20°C; Inert atmosphere; regioselective reaction;
参考文献
Alcaide, Benito; Almendros, Pedro; Alonso, Jose M.; Fernandez, Israel
Journal of Organic Chemistry, 2013 , vol. 78, # 13 p. 6688 - 6701
反应条件
oxygen; acetic acid; palladium diacetate
1.5 h; Heating;
参考文献
Mudadu, Maria S.; Singh, Ajay N.; Thummel, Randolph P.
Journal of Organic Chemistry, 2008 , vol. 73, # 17 p. 6513 - 6520
反应条件
sodium hydroxide; dipotassium hydrogenphosphate; potassium dihydrogenphosphate; D-glucose; Pseudomonas aeruginosa; magnesium sulfate; potassium nitrate; sodium chloride; calcium chloride in water
72 h; pH 7.0;
参考文献
Chakraborty; Chowdhury
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1996 , vol. 35, # 6 p. 617 - 620
反应条件
[1,3-bis(diphenylphosphino) propane] dichloronickel(II) in diethyl ether
2 h; Heating;
参考文献
Beyer, Mario; Fritscher, Joerg; Feresin, Emiliano; Schiemann, Olav
Journal of Organic Chemistry, 2003 , vol. 68, # 6 p. 2209 - 2215
反应条件
1.1: bromine; acetic acid / ethanol
2.1: n-butyllithium; chloro-trimethyl-silane / diethyl ether / 0 - 20 °C / |Inert atmosphere
2.2: 1.5 h / -78 - 0 °C
2.3: -78 - 20 °C
View Scheme
参考文献
Louillat, Marie-Laure; Patureau, Frederic W.
Organic Letters, 2013 , vol. 15, # 1 p. 164 - 167
反应条件
1: acetic acid / 0.5 h / 80 °C / Inert atmosphere
2: palladium 10 on activated carbon / 1,2,4-trimethyl benzene / 6 h / Reflux
View Scheme
参考文献
Schroegel, Pamela; Tomkeviciene, Ausra; Strohriegl, Peter; Hoffmann, Sebastian T.; Koehler, Anna; Lennartz, Christian
Journal of Materials Chemistry, 2011 , vol. 21, # 7 p. 2266 - 2273
