2-氨基-4,6-二氯嘧啶合成路线

参考文献

GLAXOSMITHKLINE LLC; AXTEN, Jeffrey, Michael; BLACKLEDGE, Charles, William; BRADY, Gerald, Patrick; FENG, Yanhoug, G.; GRANT, Seth, W.; MEDINA, Jesus, Rahul; MILLER, William, H.; ROMERIL, Stuart, P.
Patent: WO2010/59658 A1, 2010 ;
Location in patent: Page/Page column 94 ;
WO 2010/059658 A1

56-05-32-氨基-4,6-二氯嘧啶+

141-43-5乙醇胺

2846-77-72-[(2-氨基-6-氯嘧啶-4-基)氨基]乙醇

参考文献

Gibson, Colin L.; Ohta, Kyuji; Paulini, Klaus; Suckling, Colin J.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 18 p. 3025 - 3031

110-91-8吗啉+

56-05-32-氨基-4,6-二氯嘧啶

339016-18-14-氯-6-吗啉-4-基嘧啶-2-胺

参考文献

PIRAMED LIMITED; THE INSTITUTE OF CANCER RESEARCH
Patent: WO2008/125833 A1, 2008 ;
Location in patent: Page/Page column 29; 57 ;
WO 2008/125833 A1

56-05-32-氨基-4,6-二氯嘧啶+

100-51-6苯甲醇

210992-85-14-氯-6-(苯基甲氧基)-2-嘧啶胺

参考文献

LOCUS PHARMACEUTICALS, INC.
Patent: WO2008/8059 A1, 2008 ;
Location in patent: Page/Page column 85-86 ;

56-05-32-氨基-4,6-二氯嘧啶

210992-85-14-氯-6-(苯基甲氧基)-2-嘧啶胺

参考文献

Kelly, Martha; Lee, Younghee; Liu, Bin; Fujimoto, Ted; Freundlich, Joel; Dorsey, Bruce D.; Flynn, Gary A.; Husain, Arifa
Patent: US2006/270686 A1, 2006 ;
Location in patent: Page/Page column 32 ;

56-05-32-氨基-4,6-二氯嘧啶+

64-17-5乙醇

89784-02-14-氯-6-乙氧基嘧啶-2-胺

参考文献

Kitani; Sodeoka
Nippon Kagaku Zasshi, 1953 , vol. 74, p. 624
Chem.Abstr., 1954 , p. 13693

56-05-32-氨基-4,6-二氯嘧啶+

64-17-5乙醇+

141-52-6乙醇钠

89784-02-14-氯-6-乙氧基嘧啶-2-胺

参考文献

Rose; Tuey
Journal of the Chemical Society, 1946 , p. 81,84

56-05-32-氨基-4,6-二氯嘧啶