2-氨基-4,6-二氯嘧啶合成路线 （共 63 条）
反应条件
pyridine hydrogenfluoride; sodium nitrite
1.) O deg C, 20 min, 2.) 40 deg C, 1 h;
参考文献
Yoneda; Fukuhara
Tetrahedron, 1996 , vol. 52, # 1 p. 23 - 36
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethylene glycol dimethyl ether; water
T=110°C; Suzuki-Miyaura cross-coupling; 12 h;
参考文献
Yaziji, Vicente; Rodriguez, David; Gutierrez-De-Teran, Hugo; Coelho, Alberto; Caamano, Olga; Garcia-Mera, Xerardo; Brea, Jose; Loza, Maria Isabel; Cadavid, Maria Isabel; Sotelo, Eddy
Journal of Medicinal Chemistry, 2011 , vol. 54, # 2 p. 457 - 471
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in acetonitrile
参考文献
Matasi, Julius J.; Caldwell, John P.; Zhang, Hongtao; Fawzi, Ahmad; Cohen-Williams, Mary E.; Varty, Geoffrey B.; Tulshian, Deen B.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 16 p. 3670 - 3674
