1: With sulfuric acid; m-nitrobenzene sulfonic acid sodium salt in water T=60 - 130°C; 3 h; 2: With sodium hydroxide in tert-butyl methyl ether; water Product distribution / selectivity;
参考文献
Wyeth
Patent: US2007/27160 A1, 2007 ;
Location in patent: Page/Page column 66 ;
US 20070027160 A1
1: 2-bromo-5-fluorobenzenamine With 4-nitro-phenol; sulfuric acid in water T=20 - 120°C; 0.166667 - 0.5 h; 2: glycerol in water T=135 - 145°C; 3 h; 3: With potassium hydroxide; ammonia Product distribution / selectivity; more than 3 stages;
参考文献
Wyeth
Patent: US2007/299083 A1, 2007 ;
Location in patent: Page/Page column 9 ;
US 20070299083 A1
