天冬酰胺合成路线

Korpis, Katharina; Weber, Frauke; Brune, Stefanie; Wuensch, Bernhard; Bednarski, Patrick J.
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 221 - 233

56-84-8天冬酰胺+

75-36-5乙酰氯

32213-95-9L-天冬氨酸二甲酯盐酸盐

参考文献

PFIZER INC.; BAGAL, Sharanjeet Kaur; BROWN, Alan Daniel; KEMP, Mark Ian; KLUTE, Wolfgang; MARRON, Brian Edward; MILLER, Duncan Charles; SKERRATT, Sarah Elizabeth; SUTO, Mark J.; WEST, Christopher William; MALET SANZ, Laia
Patent: WO2013/114250 A1, 2013 ;
Location in patent: Page/Page column 168 ;

67-56-1甲醇+

56-84-8天冬酰胺

16856-13-6L-天冬氨酸-beta-甲酯盐酸盐+

32213-95-9L-天冬氨酸二甲酯盐酸盐

参考文献

VALORISATION-RECHERCHE SOCIETE EN COMMANDITE; LUBELL, William; JAMIESON, Andrew; BOUTARD, Nicolas; RONGA, Luisa; ST-CYR, Daniel; TURCOTTE, Daniel; CHEN, Wang
Patent: WO2010/105367 A1, 2010 ;
Location in patent: Page/Page column 35; 36; 37 ;

3130-87-8DL-天冬酰胺一水物

参考文献

Yeda Research and Development Company Ltd.
Patent: US4390722 A1, 1983 ;

56-84-8天冬酰胺

33605-73-1(S)-(-)-2-甲酰胺琥珀酸酐

参考文献

THE NUTRASWEET COMPANY
Patent: EP468063 A1, 1992 ;

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