pyridine; methanol T=40 - 50°C; Electrolysis;

pyridine; lithium tri(t-butoxy)aluminum hydride; N,N-dimethylchloromethyleniminium chloride; copper(l) iodide 1) CH3CN - THF, -30 deg C, 1 h, 2) -78 deg C, 10 min; dimethylchloromethyleniminium chloride is prepared previously in situ from oxalylchloride and DMF;

sodium tetrahydroborate; N,N-dimethylchloromethyleniminium chloride 1.) acetonitrile, THF, -30 deg C, 1 h; 2.) acetonitrile, THF, N,N-dimethylformamide, -78 deg C to -20 deg C, 2 h; Yield given. Multistep reaction;

1: (i) (cyclization), (ii) /BRN= 1420755/, (iii) (acid hydrolysis) 2: (i) NaBH4, iPrOH, (ii) MeSO2Cl, Py, (iii) Li, EtNH2 View Scheme

1: (i) (cyclization), (ii) /BRN= 1420755/, (iii) (acid hydrolysis) 2: (i) NaBH4, iPrOH, (ii) MeSO2Cl, Py, (iii) Li, EtNH2 View Scheme

暂无反应条件数据

(i) (cyclization), (ii) /BRN= 1420755/, (iii) (acid hydrolysis); Multistep reaction;