3-(3-甲酰基苯基)丙酸合成路线 （共 4 条）
反应条件
1: With potassium carbonate; Pd-Tedicyp catalyst in N,N-dimethyl-formamide
T=110°C; Heck reaction; 20 h;
2: With sodium hydroxide; water in N,N-dimethyl-formamide
T=50 - 80°C;
参考文献
Lemhadri, Mhamed; Doucet, Henri; Santelli, Maurice
Tetrahedron, 2004 , vol. 60, # 50 p. 11533 - 11540
反应条件
cerium (IV) ammonium nitrate in acetic acid
参考文献
The Upjohn Company
Patent: US3997566 A1, 1976 ;
反应条件
1: Py
2: H2SO4
3: H2 / Raney-Ni
4: (i) NaOH, MeOH, (ii) aq. HCl
View Scheme
参考文献
Higa,T.; Krubsack,A.J.
Journal of Organic Chemistry, 1975 , vol. 40, # 21 p. 3037 - 3045
反应条件
1: H2SO4
2: H2 / Raney-Ni
3: (i) NaOH, MeOH, (ii) aq. HCl
View Scheme
参考文献
Higa,T.; Krubsack,A.J.
Journal of Organic Chemistry, 1975 , vol. 40, # 21 p. 3037 - 3045
