2-氨基-4,6-二氯嘧啶-5-甲醛合成路线 (共 12 条)
反应条件
1: 61 percent / NH2OH*HCl / acetic acid; ethanol
2: 28 percent / HCl(g) / acetic acid / Heating
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参考文献
Bell, Lawrence; McGuire, H. Michael; Freeman, G. Andrew
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 41 - 44
反应条件
1: 78 percent / hydrazine hydrate / tetrahydrofuran; H2O / 0.17 h / 50 °C
2: 1.) thiourea 2.) NaOMe / 1., MeOH, 1 h, reflux 2., MeOH, 15 min, reflux
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参考文献
Seela; Steker
Helvetica Chimica Acta, 1986 , vol. 69, # 7 p. 1602 - 1613