5'-O-(苄基磺酰基)-2',3'-O-异亚丙基腺苷合成路线 （共 14 条）
反应条件
1: 73 percent / 18-crown-6 / dioxane / 60 h / Ambient temperature
2: 1.) HCl / 1.) -20 deg C, 15 h, 2.) H2O, room temp., 4 h
3: 30 percent / glacial HAc, 2 N HCl, NaNO2 / H2O / 72 h / Ambient temperature
View Scheme
参考文献
Meyer, Wilfried; Frollmann, Hartmut
Chemische Berichte, 1980 , vol. 113, # 7 p. 2530 - 2544
反应条件
1: acetone / 2 h / Heating
2: 0.5 N KOH / H2O; ethanol
3: ethanol; H2O / 0.08 h / Ambient temperature
View Scheme
参考文献
Dereu; Zingaro
Bulletin des Societes Chimiques Belges, 1982 , vol. 91, # 8 p. 685 - 694
反应条件
1: 73 percent / 18-crown-6 / dioxane / 60 h / Ambient temperature
2: 1.) HCl / 1.) -20 deg C, 15 h, 2.) H2O, room temp., 4 h
View Scheme
参考文献
Meyer, Wilfried; Frollmann, Hartmut
Chemische Berichte, 1980 , vol. 113, # 7 p. 2530 - 2544
反应条件
1: 81 percent / m-chloroperbenzoic acid / various solvent(s) / 24 h / 2 - 3 °C
2: 72.3 percent / LiN3 / dimethylformamide / 2.25 h / 74 - 80 °C
3: 74 percent / H2 / Ra-Ni / methanol / 6 h
View Scheme
参考文献
MacCoss, Malcolm; Ryu, Eung K.; White, Robert S.; Last, Robert L.
Journal of Organic Chemistry, 1980 , vol. 45, # 5 p. 788 - 794
