2,2-二甲基-5-己烯-1-醇合成路线 （共 17 条）
反应条件
1: 93 percent / triphenylphosphine, I2, pyridine / benzene / 24 h / Heating
2: 60 percent / hexaphenylditin / benzene / 15 h / Heating
3: LDA / tetrahydrofuran / 48 h / 0 °C
View Scheme
参考文献
Ashby, E. C.; Park, B.; Patil, G. S.; Gadru, K.; Gurumurthy, R.
Journal of Organic Chemistry, 1993 , vol. 58, p. 424 - 437
反应条件
pyridine in benzene
12 h; Ambient temperature;
参考文献
Ashby, E. C.; Park, B.; Patil, G. S.; Gadru, K.; Gurumurthy, R.
Journal of Organic Chemistry, 1993 , vol. 58, p. 424 - 437
反应条件
1: 60 percent / pyridinium chlorochromate, sodium acetate / CH2Cl2 / 2 h
2: 1.) LDA / 1.) ether, from -78 deg C to -40 deg C, 1 h, 2.) from -40 deg C to 0 deg C, 1 h
3: p-TsOH / benzene / 0.5 h / Heating
4: 1.) Li, liq. NH3, Ph3COH / 1.) ether, 30 min, 2.) 30 min
View Scheme
参考文献
Ashby, E. C.; Argyropoulos, J. N.
Journal of Organic Chemistry, 1985 , vol. 50, # 18 p. 3274 - 3283
反应条件
1.1: 67 percent / Et3N; SO3*py / CH2Cl2; dimethylsulfoxide / 1 h
2.1: O3 / CH2Cl2 / -78 °C
2.2: PPh3 / CH2Cl2 / 0.17 h / -78 °C
View Scheme
参考文献
Thalji, Reema K.; Roush, William R.
Journal of the American Chemical Society, 2005 , vol. 127, # 48 p. 16778 - 16779
反应条件
carbon tetrabromide; triphenylphosphine in dichloromethane
参考文献
Ashby, E. C.; Park, B.; Patil, G. S.; Gadru, K.; Gurumurthy, R.
Journal of Organic Chemistry, 1993 , vol. 58, p. 424 - 437
反应条件
pyridinium chlorochromate in dichloromethane
2 h; Ambient temperature;
参考文献
Ashby, E. C.; Park, B.; Patil, G. S.; Gadru, K.; Gurumurthy, R.
Journal of Organic Chemistry, 1993 , vol. 58, p. 424 - 437
反应条件
1: triphenylphosphine, Br2, pyridine / benzene / Heating
2: LDA / tetrahydrofuran / 72 h / 0 °C
View Scheme
参考文献
Ashby, E. C.; Park, B.; Patil, G. S.; Gadru, K.; Gurumurthy, R.
Journal of Organic Chemistry, 1993 , vol. 58, p. 424 - 437
