sodium methylate in methanol 2 h; Ambient temperature;

1: 100 percent / conc. sulphuric acid / acetic acid / Ambient temperature 2: 59 percent View Scheme

1: 4'',6''-dideoxy-4''-lt;(1S)-(1,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2-cyclohexenylaminogt;maltotriose (acarbose) With water; trifluoroacetic acid T=90°C; 1 h; 2: acetic anhydride With pyridine T=90°C; 1 h; Product distribution / selectivity;

1: 4'',6''-dideoxy-4''-lt;(1S)-(1,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2-cyclohexenylaminogt;maltotriose (acarbose) With water; trifluoroacetic acid T=90°C; 1 h; 2: acetic anhydride With pyridine T=90°C; 1 h; Product distribution / selectivity;

dextrosucrase B742CB; acetic acid-pyridine in water T=27°C; pH=5.2; 120 h; Product distribution; Further Variations:Reagents;

dextrosucrase B742CB; acetic acid-pyridine in water T=27°C; pH=5.2; 120 h; Product distribution; Further Variations:Reagents;

pyridine T=20°C; Acetylation; 24 h;