(E)-11-十六碳烯-1-醇乙酸酯合成路线 （共 36 条）
反应条件
1: 1.) Na2SO3, NaHCO3 / 1.) H2O, 10 h, 2.) 1 h
2: Et3N / CH2Cl2 / 1 h / Ambient temperature
3: 1.) Mg / 1.) Et2O, 2.) reflux, 1 h
4: (AcO)2Cu / acetic acid; H2O / 0.67 h / Heating
5: 85percent hydrazine hydrate / butan-1-ol / Heating
6: O2, CuCl / pyridine
7: LiAlH4 / bis-(2-methoxy-ethyl) ether / 15 °C
8: acetic acid / 10 h / 50 °C
View Scheme
参考文献
Oprean, I.; Ciupe, Hilke; Gansca, Lucia; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 2 p. 283 - 289
反应条件
1: Et3N / CH2Cl2 / 1 h / Ambient temperature
2: 1.) Mg / 1.) Et2O, 2.) reflux, 1 h
3: (AcO)2Cu / acetic acid; H2O / 0.67 h / Heating
4: 85percent hydrazine hydrate / butan-1-ol / Heating
5: O2, CuCl / pyridine
6: LiAlH4 / bis-(2-methoxy-ethyl) ether / 15 °C
7: acetic acid / 10 h / 50 °C
View Scheme
参考文献
Oprean, I.; Ciupe, Hilke; Gansca, Lucia; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 2 p. 283 - 289
反应条件
1: 1.) Mg / 1.) Et2O, 2.) reflux, 1 h
2: (AcO)2Cu / acetic acid; H2O / 0.67 h / Heating
3: 85percent hydrazine hydrate / butan-1-ol / Heating
4: O2, CuCl / pyridine
5: LiAlH4 / bis-(2-methoxy-ethyl) ether / 15 °C
6: acetic acid / 10 h / 50 °C
View Scheme
参考文献
Oprean, I.; Ciupe, Hilke; Gansca, Lucia; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 2 p. 283 - 289
反应条件
1: 85percent hydrazine hydrate / butan-1-ol / Heating
2: O2, CuCl / pyridine
3: LiAlH4 / bis-(2-methoxy-ethyl) ether / 15 °C
4: acetic acid / 10 h / 50 °C
View Scheme
参考文献
Oprean, I.; Ciupe, Hilke; Gansca, Lucia; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 2 p. 283 - 289
反应条件
1: (AcO)2Cu / acetic acid; H2O / 0.67 h / Heating
2: 85percent hydrazine hydrate / butan-1-ol / Heating
3: O2, CuCl / pyridine
4: LiAlH4 / bis-(2-methoxy-ethyl) ether / 15 °C
5: acetic acid / 10 h / 50 °C
View Scheme
参考文献
Oprean, I.; Ciupe, Hilke; Gansca, Lucia; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 2 p. 283 - 289
反应条件
1: O2, CuCl / pyridine
2: LiAlH4 / bis-(2-methoxy-ethyl) ether / 15 °C
3: acetic acid / 10 h / 50 °C
View Scheme
参考文献
Oprean, I.; Ciupe, Hilke; Gansca, Lucia; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 2 p. 283 - 289
反应条件
1: Li2CuCl4 / tetrahydrofuran / 5 h, -20 deg C; 8 h, RT
2: LiAlH4 / bis-(2-methoxy-ethyl) ether; tetrahydrofuran / 140 °C
3: acetic acid / 48 h / Ambient temperature
View Scheme
参考文献
Pop, Lidia; Oprean, I.; Barabas, A.; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 5/6 p. 867 - 878
反应条件
1: pyridine / 5 h / 0 °C
2: NaBr / dimethylformamide / 2 h / 75 °C
3: Li2CuCl4 / tetrahydrofuran / 5 h, -20 deg C; 8 h, RT
4: LiAlH4 / bis-(2-methoxy-ethyl) ether; tetrahydrofuran / 140 °C
5: acetic acid / 48 h / Ambient temperature
View Scheme
参考文献
Pop, Lidia; Oprean, I.; Barabas, A.; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 5/6 p. 867 - 878
反应条件
1: NaBr / dimethylformamide / 2 h / 75 °C
2: Li2CuCl4 / tetrahydrofuran / 5 h, -20 deg C; 8 h, RT
3: LiAlH4 / bis-(2-methoxy-ethyl) ether; tetrahydrofuran / 140 °C
4: acetic acid / 48 h / Ambient temperature
View Scheme
参考文献
Pop, Lidia; Oprean, I.; Barabas, A.; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 5/6 p. 867 - 878
反应条件
1: Li2CuCl4 / tetrahydrofuran / 5 h, -20 deg C; 8 h, RT
2: LiAlH4 / bis-(2-methoxy-ethyl) ether; tetrahydrofuran / 140 °C
3: acetic acid / 48 h / Ambient temperature
View Scheme
参考文献
Pop, Lidia; Oprean, I.; Barabas, A.; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 5/6 p. 867 - 878
