Α-羟基-Α-甲苄基甲苯酮合成路线 （共 41 条）
反应条件
carbon monoxide; sodium methylate; methyl iodide T=20°C; 20 h;
参考文献
Miura, Masahiro; Akase, Fumiaki; Shinohara, Masato; Nomura, Masakatsu
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 1021 - 1026
反应条件
1: 23 percent / Ni / various solvent(s) / 36 h / Ambient temperature 2: 1.) Cu / 1.) THF, 0 deg C, 3 h, 2.) a. 0 deg C, 3 h, b. RT, 10 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 10 p. 2381 - 2383
反应条件
rubidium hydroxide in tetrahydrofuran T=67°C; 15 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 259 - 262
反应条件
Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 21, p. 1017 - 1020
反应条件
1: 15 percent / Na, PhMe2SiLi / tetrahydrofuran / 20 h 2: 75 percent / diethyl ether; tetrahydrofuran / 1.5 h / -78 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 7 p. 1215 - 1228
反应条件
1: potassium tert-butylate / tetrahydrofuran / 0 °C 2: caesium carbonate; triethyl phosphite; oxygen / dimethyl sulfoxide / 24 h / 25 °C / 760.05 Torr / |Schlenk technique View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 53, # 2 p. 548 - 552
Angew. Chem., , vol. 53, # 2 p. 558 - 562,5
反应条件
1: 94 percent / 4 h / Heating 2: 1.)Diisopropylamine, n-BuLi, 2.)HCl/H2O / 1)THF, -100 deg C, 20 min; 2)reflux View Scheme
参考文献
Journal of Organic Chemistry, , vol. 45, # 20 p. 3994 - 3998
反应条件
copper 1.) THF, 0 deg C, 3 h, 2.) a. 0 deg C, 3 h, b. RT, 10 h; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 53, # 10 p. 2381 - 2383
反应条件
(+)-(2S,8aS)-(camphorylsulfonyl)oxaziridine; sodium hexamethyldisilazane 1.) THF, -78 deg C, 45 min, 2.) reflux, 4 h; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 54, # 8 p. 2021 - 2024
反应条件
tetra-(n-butyl)ammonium iodide in N,N-dimethyl-formamide (electrolysis); Further byproducts given;
参考文献
Bulletin de la Societe Chimique de France, , p. 2547 - 2555
