2-哌嗪酮合成路线

参考文献

Martini, Elisabetta; Ghelardini, Carla; Dei, Silvia; Guandalini, Luca; Manetti, Dina; Melchiorre, Michele; Norcini, Monica; Scapecchi, Serena; Teodori, Elisabetta; Romanelli, Maria Novella
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 3 p. 1431 - 1443

5625-67-22-哌嗪酮+

123-62-6丙酸酐

65493-55-24-丙酰基-2-哌嗪酮

参考文献

Martini, Elisabetta; Ghelardini, Carla; Dei, Silvia; Guandalini, Luca; Manetti, Dina; Melchiorre, Michele; Norcini, Monica; Scapecchi, Serena; Teodori, Elisabetta; Romanelli, Maria Novella
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 3 p. 1431 - 1443

5625-67-22-哌嗪酮+

79286-73-0

87939-12-6

参考文献

Matsumoto; Miyamoto; Minamida; Nishimura; Egawa
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 292 - 301

5625-67-22-哌嗪酮+

7693-46-1对硝基苯基氯甲酸酯

880093-94-7

参考文献

Ikeura, Yoshinori; Hashimoto, Tadatoshi; Nishida, Haruyuki; Shirai, Junya; Sakauchi, Nobuki
Patent: US2006/142337 A1, 2006 ;
Location in patent: Page/Page column 68 ;
US 20060142337 A1

5625-67-22-哌嗪酮+

541-41-3氯甲酸乙酯

59701-99-4

参考文献

ELI LILLY AND COMPANY; LAMAS-PETEIRA, Carlos; RICHARDS, Simon, James; SAPMAZ, Selma; WALTER, Magnus, Wilhelm
Patent: WO2012/74769 A1, 2012 ;
Location in patent: Page/Page column 23 ;
WO 2012/074769 A1

5625-67-22-哌嗪酮+

4774-14-52,6-二氯吡嗪

61655-86-5

参考文献

Merck and Co., Inc.
Patent: US4163849 A1, 1979 ;