4-溴-3-甲氧基苯甲酸合成路线 （共 14 条）
反应条件
4-(N,N-dimethlyamino)pyridine; 1,1'-carbonyldiimidazole in N,N-dimethyl-formamide
T=20°C;
参考文献
Mineno, Tomoko; Ueno, Tasuku; Urano, Yasuteru; Kojima, Hirotatsu; Nagano, Tetsuo
Organic Letters, 2006 , vol. 8, # 26 p. 5963 - 5966
反应条件
1.1: 86 percent / CDI; DMAP / dimethylformamide / 20 °C
2.1: t-BuLi / tetrahydrofuran / 1 h / -100 °C
2.2: 42 percent / aq. HCl / tetrahydrofuran / 0.17 h
View Scheme
参考文献
Mineno, Tomoko; Ueno, Tasuku; Urano, Yasuteru; Kojima, Hirotatsu; Nagano, Tetsuo
Organic Letters, 2006 , vol. 8, # 26 p. 5963 - 5966
反应条件
1.1: 86 percent / CDI; DMAP / dimethylformamide / 20 °C
2.1: t-BuLi / tetrahydrofuran / 1 h / -100 °C
2.2: 42 percent / aq. HCl / tetrahydrofuran / 0.17 h
3.1: 90 percent / aq. NaOH / 2 h / Heating
View Scheme
参考文献
Mineno, Tomoko; Ueno, Tasuku; Urano, Yasuteru; Kojima, Hirotatsu; Nagano, Tetsuo
Organic Letters, 2006 , vol. 8, # 26 p. 5963 - 5966
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in 1,4-dioxane; hexane
T=70°C; 1 h;
参考文献
Hadida Ruah, Sara Sabina; Kallel, Edward Adam; Miller, Mark Thomas; Arumugam, Vijayalaksmi; McCartney, Jason; Anderson, Corey; Grootenhuis, Peter Diederik Jan; Jiang, Licong
Patent: US2012/196869 A1, 2012 ;
Location in patent: Paragraph 0365; 0366 ;
US 20120196869 A1
