1-(2-甲基苯基)-1,3-丁烷二酮合成路线 （共 3 条）
反应条件
sodium hydride in diethyl ether; ethanol
46 h; Ambient temperature;
参考文献
Hornback, Joseph M.; Poundstone, Melani L.; Vadlamani, Bhanumathi; Graham, Susan M.; Gabay, Julie; Patton, Shelly T.
Journal of Organic Chemistry, 1988 , vol. 53, # 24 p. 5597 - 5601
反应条件
L-proline
T=20°C; 96 h;
参考文献
Shen, Zongxuan; Li, Bin; Wang, Lu; Zhang, Yawen
Tetrahedron Letters, 2005 , vol. 46, # 50 p. 8785 - 8788
反应条件
1.1: dichloro(cycloocta-1,5-diene)palladium(II); 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; magnesium chloride; triethylamine / 1,4-dioxane / 100 °C / |Glovebox; |Inert atmosphere
1.2: 100 °C / |Glovebox; |Inert atmosphere
1.3: 18 h / 100 °C
2.1: hydrogenchloride / water / 1 h / 80 °C
View Scheme
参考文献
Korsager, Signe; Nielsen, Dennis U.; Taaning, Rolf H.; Lindhardt, Anders T.; Skrydstrup, Troels
Chemistry - A European Journal, 2013 , vol. 19, # 52 p. 17687 - 17691
