反应条件
1: 67 percent / NaOEt / ethanol / 40 - 45 °C
2: 94 percent / Br2, AcONa*3H2O / CHCl3 / 1 h
3: 70 percent / pyridine / 1.) 18 h, r.t., 2.) 1 h, reflux
4: 1.) NaNO2, 40 percent H2SO4, 2.) CuSO4*5H2O, NaCl / 1.) water, 30 min, -10 deg C, 2.) water, 40 min, r.t.
5: 96 percent / H2, triethylamine / 10 percent Pd-C / ethanol / 760 Torr
View Scheme
参考文献
Katsuura; Yamaguchi; Sakai; Mitsuhashi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1518 - 1527
