3-氰基-6-(2-呋喃)-2-羟基吡啶合成路线 （共 4 条）
反应条件
potassium carbonate in dimethyl sulfoxide
T=120 - 140°C; 21 h;
参考文献
Harada, Hitoshi; Asano, Osamu; Miyazawa, Shuhei; Ueda, Masato; Yasuda, Masahiro; Yasuda, Nobuyuki
Patent: US2004/6082 A1, 2004 ;
Location in patent: Page/Page column 22-23 ;
反应条件
potassium carbonate in dimethyl sulfoxide
参考文献
Eisai Co., Ltd.
Patent: EP1308441 A1, 2003 ;
反应条件
water; sodium acetate
0.5 h; Reflux;
参考文献
Alnajjar, Abdul-Aziz; Abdelkhalik, Mervat Mohammed; Al-Enezi, Amal; Elnagdi, Mohamed Hilmy
Molecules, 2009 , vol. 14, # 1 p. 68 - 77
反应条件
1: |Reflux
2: 1,4-diaza-bicyclo[2.2.2]octane / ethanol / 20 °C / |Reflux
View Scheme
参考文献
Wang, Ning-Yu; Zuo, Wei-Qiong; Xu, Ying; Gao, Chao; Zeng, Xiu-Xiu; Zhang, Li-Dan; You, Xin-Yu; Peng, Cui-Ting; Shen, Yang; Yang, Sheng-Yong; Wei, Yu-Quan; Yu, Luo-Ting
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 6 p. 1581 - 1588
