tris-(dibenzylideneacetone)dipalladium(0); t-Bu Brett Phos; tri[2-(2-methoxyethoxy)ethyl]amine in toluene T=130°C; 16 h; Inert atmosphere;

sodium hydrogencarbonate in dichloromethane; water; toluene T=0 - 20°C;

1: triethylamine / dichloromethane / 14 h / -78 °C / |Inert atmosphere 2: tri[2-(2-methoxyethoxy)ethyl]amine; tris-(dibenzylideneacetone)dipalladium(0); t-Bu Brett Phos / toluene / 16 h / 130 °C / |Inert atmosphere View Scheme

tributylphosphine in dichloromethane T=-78 - 20°C; P=760 Torr; Product distribution;

in 1,2-dichloro-ethane T=70 - 83°C;