8-苯基-1,4-二噁螺[4,5]癸烷-8-羧醛合成路线 (共 2 条)
反应条件
1: With diisobutylaluminium hydride in toluene
T=50°C; 0.222222 h; Flow reactor;
2: With water; tartaric acid disodium salt in toluene
T=0°C; chemoselective reaction;
参考文献
Munoz, Juan De M.; Alcazar, Jesus; De La Antonio, Hoz; Diaz-Ortiz, Angel
Tetrahedron Letters, 2011 , vol. 52, # 46 p. 6058 - 6060
反应条件
sodium tetrahydroborate in tetrahydrofuran; methanol
T=20°C; 1 h;
参考文献
Wu, Yong-Jin; He, Huan; Bertekap, Robert; Westphal, Ryan; Lelas, Snjezana; Newton, Amy; Wallace, Tanya; Taber, Matthew; Davis, Carl; MacOr, John E.; Bronson, Joanne
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 8 p. 2217 - 2228