反应条件
1: (i) aq. HCl, (ii) /BRN= 1718733/, H2SO4, benzene
2: TsOH
3: (i) NaH, DMF, benzene, (ii) /BRN= 1774399/
4: aq. NaOH / ethanol
View Scheme
参考文献
Jones; Holtz; Bicking; Cragoe Jr.; Mandel; Kuehl Jr.
Journal of Medicinal Chemistry, 1977 , vol. 20, # 1 p. 44 - 48