(8S-顺式)-8-乙酰基-10-[(3-氨基-2,3,6-三去氧-alpha-L-阿拉伯吡喃糖基)氧基]-7,8,9,10-四氢-6,8,11-三羟基-1-甲氧基并四苯-5,12-二酮盐酸盐合成路线 （共 7 条）
反应条件
1: With sodium hydroxide; water T=30°C; 0.5 h; 2: With hydrogenchloride; water pH=7;
参考文献
US2007/142309 A1, ;
Page/Page column 6 ;
反应条件
1: 1.) NaN3; 2.) LiAlH4 / 1.) DMF, 140 deg C, 2.5 h; 2.) ether, 0 deg C, 15 min 2: 95 percent / triethylamine / CH2Cl2 / 0.08 h / 20 °C 3: 100 percent / pyridine / 16 h / 20 °C 4: 41 percent / TsOH / benzene; CH2Cl2 / 2 h / Heating 5: 1.) 0.1M aq. NaOH; 2.) HCl / 1.) dioxane, 20 deg C, 1h; 2.) dichloromethane View Scheme
参考文献
Carbohydrate Research, , vol. 79, p. 193 - 204
反应条件
1: 41 percent / TsOH / benzene; CH2Cl2 / 2 h / Heating 2: 1.) 0.1M aq. NaOH; 2.) HCl / 1.) dioxane, 20 deg C, 1h; 2.) dichloromethane View Scheme
参考文献
Carbohydrate Research, , vol. 79, p. 193 - 204
反应条件
1: 95 percent / triethylamine / CH2Cl2 / 0.08 h / 20 °C 2: 100 percent / pyridine / 16 h / 20 °C 3: 41 percent / TsOH / benzene; CH2Cl2 / 2 h / Heating 4: 1.) 0.1M aq. NaOH; 2.) HCl / 1.) dioxane, 20 deg C, 1h; 2.) dichloromethane View Scheme
参考文献
Carbohydrate Research, , vol. 79, p. 193 - 204
反应条件
1: 100 percent / pyridine / 16 h / 20 °C 2: 41 percent / TsOH / benzene; CH2Cl2 / 2 h / Heating 3: 1.) 0.1M aq. NaOH; 2.) HCl / 1.) dioxane, 20 deg C, 1h; 2.) dichloromethane View Scheme
参考文献
Carbohydrate Research, , vol. 79, p. 193 - 204
反应条件
1: 77 percent / Zn/CuSO4*5H2O / dimethylformamide; H2O; acetic acid / 20 h / 0 °C 2: 1.) NaN3; 2.) LiAlH4 / 1.) DMF, 140 deg C, 2.5 h; 2.) ether, 0 deg C, 15 min 3: 95 percent / triethylamine / CH2Cl2 / 0.08 h / 20 °C 4: 100 percent / pyridine / 16 h / 20 °C 5: 41 percent / TsOH / benzene; CH2Cl2 / 2 h / Heating 6: 1.) 0.1M aq. NaOH; 2.) HCl / 1.) dioxane, 20 deg C, 1h; 2.) dichloromethane View Scheme
参考文献
Carbohydrate Research, , vol. 79, p. 193 - 204
反应条件
hydrogenchloride; sodium hydroxide 1.) dioxane, 20 deg C, 1h; 2.) dichloromethane; Multistep reaction;
参考文献
Carbohydrate Research, , vol. 79, p. 193 - 204
