3,3,3-三氟-2-(三氟甲基)丙酸合成路线 (共 16 条)
反应条件
water in tetrahydrofuran T=20°C; 4 h;
参考文献
Wiebe, Donald A.; Burton, Donald J.
Journal of Fluorine Chemistry, 2012 , vol. 139, p. 4 - 11
反应条件
water in acetone T=20°C; 72 h;
参考文献
Luzina, Elena L.; Popov, Anatoliy V.
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 12 p. 4944 - 4953
反应条件
cesium fluoride in acetonitrile T=20°C; 120 h;
参考文献
Zeifman, Yu. V.; Postovoi, S. A.; Knunyants, I. L.
Doklady Chemistry, 1982 , vol. 265, p. 212 - 215
Dokl. Akad. Nauk SSSR Ser. Khim., 1982 , vol. 265, # 2 p. 347 - 351
参考文献
Simonyan, L. A.; Safronova, Z. V.; Gambaryan, N. P.; Antipin, M. Yu.; Struchkov, Yu. T.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1980 , vol. 29, # 2 p. 272 - 277
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1980 , # 2 p. 358 - 364
反应条件
moisture; Copper(I) trifluoromethanethiolate in acetonitrile 1.) -78 deg C, 2 h, 2.) from 55 deg C to 60 deg C, 4 h; Further byproducts given. Title compound not separated from byproducts;
参考文献
Journal of Fluorine Chemistry, , vol. 63, # 3 p. 253 - 264
参考文献
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , p. 1353,1360;engl.Ausg.S.1387,1393
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 7, p. 1529 - 1533
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 7, p. 1645 - 1650
反应条件
(i) (pyrolysis), (ii) H2SO4; Multistep reaction;
参考文献
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , p. 1435 - 1438
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , p. 1573 - 1576
参考文献
Aktaev,N.P. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1977 , vol. 26, p. 1018 - 1023
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1977 , vol. 26, p. 1112 - 1117