2-苄基-3-氧代-3-苯基丙酸乙酯合成路线 （共 23 条）
反应条件
1.) 80 deg C, 4 h, 2.) 110 deg C, 2 h, 3.) 130 deg C, 5 h;
参考文献
Vartanyan, S. A.; Vartanyan, R. S.; Karamyan, S. A.; Avetyan, L. O.; Apoyan, N. A.; Melkonyan, Zh. S.
Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 7 p. 470 - 473
Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 7 p. 821 - 825
反应条件
1.) 80 deg C, 4 h, 2.) 110 deg C, 2 h, 3.) 130 deg C, 5 h;
参考文献
Pharmaceutical Chemistry Journal, , vol. 19, # 7 p. 470 - 473
Khimiko-Farmatsevticheskii Zhurnal, , vol. 19, # 7 p. 821 - 825
反应条件
in water; N,N-dimethyl-formamide T=200°C; 0.333333 h; microwave irradiation;
参考文献
Curran, Dennis P.; Zhang, Qisheng
Advanced Synthesis and Catalysis, 2003 , vol. 345, # 3 p. 329 - 332
反应条件
potassium carbonate in tetrahydrofuran 6 h;
参考文献
Synthetic Communications, , vol. 18, # 11 p. 1213 - 1224
反应条件
formic acid; triethylamine; N-(2-amino-ethyl)-4-methyl-benzenesulphonamide; [Ru2(p-PriC6H4Me)2(μ-Cl)Cl]2 in dichloromethane
T=30°C; 9 h;
参考文献
Xue, Dong; Chen, Ying-Chun; Cui, Xin; Wang, Qi-Wei; Zhu, Jin; Deng, Jin-Gen
Journal of Organic Chemistry, 2005 , vol. 70, # 9 p. 3584 - 3591
反应条件
polystyrene-trityllithium in tetrahydrofuran
Ambient temperature;
参考文献
Cohen, B. J.; Kraus, M. A.; Patchornik, A.
Journal of the American Chemical Society, 1981 , vol. 103, # 25 p. 7620 - 7629
反应条件
1: diazoacetic acid ethyl ester; PhC(O)TMS With lithium diisopropyl amide in tetrahydrofuran
T=-78°C; 0.5 h;
2: benzyl bromide in tetrahydrofuran
T=23°C; 16 h; Further stages.;
参考文献
Galliford, Chris V.; Scheidt, Karl A.
Chemical Communications, 2008 , # 16 p. 1926 - 1928
反应条件
10 Pd/C; triethylamine
T=100°C; Heck Reaction; 4 h;
参考文献
Kim, Hyun-Soo; Lee, Sang-Jin; Choi, Boram; Yoon, Cheol Min
Synthesis (Germany), 2012 , vol. 44, # 20 p. 3161 - 3164
反应条件
sodium hydride in tetrahydrofuran
T=20°C; Inert atmosphere;
参考文献
Jiang, Yaojia; Chan, Wei Chuen; Park, Cheol-Min
Journal of the American Chemical Society, 2012 , vol. 134, # 9 p. 4104 - 4107
反应条件
1: α-acetylbenzenepropanoic acid ethyl ester With sodium hydride in tetrahydrofuran
T=20°C; 0.666667 h;
2: PhCOBt in tetrahydrofuran
T=20°C; 14 h;
3: With ammonium hydroxide; ammonium chloride in tetrahydrofuran; water
1 h; Heating;
参考文献
Katritzky, Alan R.; Wang, Zuoquan; Wang, Mingyi; Wilkerson, Chavon R.; Hall, C. Dennis; Akhmedov, Novruz G.
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6617 - 6622
