1-(溴甲基)-3-氯-2-硝基苯合成路线 （共 4 条）
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in tetrachloromethane
8 h; Heating / reflux;
参考文献
NICHOLAS PIRAMAL INDIA LIMITED
Patent: WO2006/51477 A2, 2006 ;
Location in patent: Page/Page column 83 ;
反应条件
1: 54 percent / fuming nitric acid / 0.75 h / 20 °C
2: 96 percent / H2SO4 / H2O
3: 1.) NaNO2, conc. HCl / 1.) C2H5OH, 2.) 70 deg C
4: N-bromosuccinimide, benzoylperoxide / CCl4 / 30 h / 80 °C / Irradiation
View Scheme
参考文献
Ahmad, Arshad; Dunbar, Linda J.; Green, Iain G.; Harvey, Ian W.; Shepherd, Thomas; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 19 p. 2751 - 2758
反应条件
1: 1.) NaNO2, conc. HCl / 1.) C2H5OH, 2.) 70 deg C
2: N-bromosuccinimide, benzoylperoxide / CCl4 / 30 h / 80 °C / Irradiation
View Scheme
参考文献
Ahmad, Arshad; Dunbar, Linda J.; Green, Iain G.; Harvey, Ian W.; Shepherd, Thomas; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 19 p. 2751 - 2758
反应条件
1: 96 percent / H2SO4 / H2O
2: 1.) NaNO2, conc. HCl / 1.) C2H5OH, 2.) 70 deg C
3: N-bromosuccinimide, benzoylperoxide / CCl4 / 30 h / 80 °C / Irradiation
View Scheme
参考文献
Ahmad, Arshad; Dunbar, Linda J.; Green, Iain G.; Harvey, Ian W.; Shepherd, Thomas; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 19 p. 2751 - 2758
