4-苄氧基-3-甲氧基苯甲酸甲酯合成路线 （共 13 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=100°C; 3 h;
参考文献
Ehlert, Jan; Herz, Thomas; Krauss, Rolf; Kubbutat, Micheal; Lang, Martin; Pegoraro, Stefano; Schachtele, Christoph; Totzke, Frank; Zirrgiebel, Ute
Patent: US2007/149523 A1, 2007 ;
Location in patent: Page/Page column 13 ;
反应条件
potassium carbonate in acetone 16 h; Heating / reflux;
参考文献
WYETH
Patent: US2007/208164 A1, 2007 ;
Location in patent: Page/Page column 14 ;
反应条件
potassium carbonate in acetonitrile T=20°C; 8 h; Inert atmosphere;
参考文献
Yanagita, Hiroshi; Yamamoto, Norio; Fuji, Hideyoshi; Liu, Xinli; Ogata, Masakazu; Yokota, Mizuho; Takaku, Hiroshi; Hasegawa, Hideki; Odagiri, Takato; Tashiro, Masato; Hoshino, Tyuji
ACS Chemical Biology, 2012 , vol. 7, # 3 p. 552 - 562
反应条件
hydrogen; palladium on activated charcoal in various solvent(s) T=20°C; P=760 Torr; 6 h;
参考文献
Chandrasekhar; Shyamsunder; Chandrashekar; Narsihmulu
Synlett, 2004 , # 3 p. 522 - 524
反应条件
1: 82.6 percent / nitric acid / tin(IV) chloride / CH2Cl2 / 0.17 h / -20 °C 2: 95.8 percent / sodium borohydride / nickel(II) chloride hexahydrate / methanol; CH2Cl2 / 0.5 h / 0 - 5 °C View Scheme
参考文献
Pham, Helen Trinh; Hanson, Robert N.; Olmsted, Sandra L.; Kozhushnyan, Anton; Visentin, Adam; Weglinsky, Paul J.; Massero, Chris; Bailey, Kristen
Tetrahedron Letters, 2011 , vol. 52, # 10 p. 1053 - 1056
反应条件
1: 78 percent / SnCl4; HNO3 / CH2Cl2 / 0.08 h / -78 °C 2: 83 percent / LiOH / tetrahydrofuran; H2O; methanol / 12 h / 20 °C View Scheme
参考文献
Kamal, Ahmed; Ramesh; Srinivas; Ramulu; Laxman; Rehana, Tasneem; Deepak; Achary; Nagarajaram
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 20 p. 5427 - 5436
反应条件
1: 82.6 percent / nitric acid / tin(IV) chloride / CH2Cl2 / 0.17 h / -20 °C 2: 95.8 percent / sodium borohydride / nickel(II) chloride hexahydrate / methanol; CH2Cl2 / 0.5 h / 0 - 5 °C 3: 98 percent / aq. sodium hydroxide / methanol / 1 h / Heating View Scheme
参考文献
Wang, Tiansheng; Lui, Alfred S.; Cloudsdale, Ian S.
Organic Letters, 1999 , vol. 1, # 11 p. 1835 - 1837
反应条件
sodium hydroxide in methanol 4 h; Heating / reflux;
参考文献
PROTEOTECH, INC.
Patent: WO2005/113489 A1, 2005 ;
Location in patent: Page/Page column 93 ;
反应条件
1: nitric acid / acetic acid 2: sodium tetrahydroborate; NiII chloride hexahydrate 3: formamide View Scheme
参考文献
Pham, Helen Trinh; Hanson, Robert N.; Olmsted, Sandra L.; Kozhushnyan, Anton; Visentin, Adam; Weglinsky, Paul J.; Massero, Chris; Bailey, Kristen
Tetrahedron Letters, 2011 , vol. 52, # 10 p. 1053 - 1056
反应条件
1: nitric acid / acetic acid 2: sodium tetrahydroborate; NiII chloride hexahydrate 3: formamide 4: thionyl chloride / N,N-dimethyl-formamide View Scheme
参考文献
Pham, Helen Trinh; Hanson, Robert N.; Olmsted, Sandra L.; Kozhushnyan, Anton; Visentin, Adam; Weglinsky, Paul J.; Massero, Chris; Bailey, Kristen
Tetrahedron Letters, 2011 , vol. 52, # 10 p. 1053 - 1056
