4-[(3,4-二氯苄基)氧基]苯羧酸合成路线 （共 6 条）
反应条件
1: With water; lithium hydroxide hydrate in tetrahydrofuran 4 h; Reflux; 2: With hydrogenchloride in water
参考文献
PFIZER LIMITED; BROWN, Alan, Daniel; RAWSON, David, James; STORER, Robert, Ian; SWAIN, Nigel, Alan
Patent: WO2012/7868 A2, 2012 ;
Location in patent: Page/Page column 76 ;
参考文献
Journal of Medicinal Chemistry, , vol. 20, # 11 p. 1388 - 1393
反应条件
1: NaOEt 2: aq. NaOH View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 20, # 11 p. 1388 - 1393
反应条件
1: NaOEt 2: aq. NaOH View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 20, # 11 p. 1388 - 1393
反应条件
1: sodium hydride / tetrahydrofuran; mineral oil / 48 h / 20 °C 2: water; lithium hydroxide hydrate / tetrahydrofuran / 4 h / Reflux View Scheme
反应条件
1: sodium hydride / tetrahydrofuran; mineral oil / 48 h / 20 °C 2: water; lithium hydroxide hydrate / tetrahydrofuran / 4 h / Reflux View Scheme
