2-氯-4-三氟甲基苯甲醇合成路线 （共 4 条）
反应条件
borane-THF T=0 - 30°C; 1 h;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2006/57448 A1, 2006 ;
Location in patent: Page/Page column 163 ;
反应条件
pyridine; thionyl chloride in tetrahydrofuran; diethyl ether T=0 - 30°C; 15 h;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2007/18314 A2, 2007 ;
Location in patent: Page/Page column 158 ;
WO 2007/018314 A2
反应条件
carbon tetrabromide; triphenylphosphine in tetrahydrofuran T=0 - 30°C; 2 h;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2006/57448 A1, 2006 ;
Location in patent: Page/Page column 163-164 ;
反应条件
triphenylphosphine in tetrahydrofuran; diethyl ether; hexane
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP1829863 A1, 2007 ;
