DL-2-氨基-2-苯基丙酸合成路线 （共 23 条）
反应条件
1: 80 °C / unter Druck 2: hydrochloric acid View Scheme
参考文献
Chemische Berichte, , vol. 39, p. 1195
反应条件
1: 1.) 18-crown-6, KH / 1.) THF, 2.) THF, RT, 1.5 h 2: 63 percent / 5 N HCl / 24 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 22 p. 4446 - 4453
反应条件
1: ammonium cerium (IV) nitrate / water; acetonitrile / 1 h / 0 °C / |Inert atmosphere 2: sodium hydroxide; water / 1,4-dioxane / 20 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Chemical Communications, , vol. 49, # 84 p. 9734 - 9736
反应条件
1: With water; sodium hydroxide in 1,4-dioxane 20 h; Inert atmosphereReflux; 2: With hydrogenchloride in water
参考文献
Chemical Communications, , vol. 49, # 84 p. 9734 - 9736
反应条件
1.1: triethylamine / dichloromethane; hexane / 0.17 h / -45 °C / |Inert atmosphere 1.2: 17.3 h / -45 - 20 °C / |Inert atmosphere 2.1: C29H37N2O2P / 24 h / 20 °C 3.1: potassium permanganate; potassium hydroxide; potassium dihydrogenphosphate / tert-butyl alcohol / 3.08 h / 20 °C 4.1: hydrogenchloride / water; tetrahydrofuran / 15 h / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 135, # 44 p. 16348 - 16351
反应条件
1: C29H37N2O2P / 24 h / 20 °C 2: potassium permanganate; potassium hydroxide; potassium dihydrogenphosphate / tert-butyl alcohol / 3.08 h / 20 °C 3: hydrogenchloride / water; tetrahydrofuran / 15 h / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 135, # 44 p. 16348 - 16351
反应条件
hydrogenchloride; methyloxirane 1.) water, reflux, 1h, 2.) ethanol, reflux, 15 min; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 30, # 30 p. 3913 - 3914
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 18, p. 273 - 274
反应条件
1: alcoholic ammonia / 60 - 80 °C / im geschlossenen Gefaess 2: fuming hydrochloric acid / 20 °C / Behandeln dann mit verd. Salzsaeure und Alkohol View Scheme
参考文献
Chemische Berichte, , vol. 14, p. 1980
参考文献
Chemische Berichte, , vol. 14, p. 1980
