4-甲基-1-戊炔-3-醇合成路线 （共 30 条）
反应条件
1: acetylene With n-butyllithium in tetrahydrofuran; hexane T=-30°C; 0.5 h; 2: isobutyraldehyde in tetrahydrofuran; hexane T=-30°C; 1 h; Further stages.;
参考文献
Kudoh, Takayuki; Mori, Tomoko; Shirahama, Mitsuhito; Yamada, Masashi; Ishikawa, Teruhiko; Saito, Seiki; Kobayashi, Hisayoshi
Journal of the American Chemical Society, 2007 , vol. 129, # 16 p. 4939 - 4947
反应条件
in tetrahydrofuran T=0 - 20°C; 5.5 h;
参考文献
Wang, Christy; Sperry, Jonathan
Tetrahedron, 2013 , vol. 69, # 23 p. 4563 - 4577
反应条件
in tetrahydrofuran T=0°C; 3 h;
参考文献
Angewandte Chemie - International Edition, , vol. 47, # 20 p. 3777 - 3780
反应条件
in tetrahydrofuran T=0 - 20°C; 2 h;
参考文献
Braverman, Samuel; Pechenick-Azizi, Tatiana; Gottlieb, Hugo E.; Sprecher, Milon
Synthesis, 2011 , # 11 p. 1741 - 1750
反应条件
potassium hydroxide T=70°C; 120 h;
参考文献
Gazzetta Chimica Italiana, , vol. 124, # 6 p. 241 - 248
参考文献
Zhurnal Obshchei Khimii, , vol. 25, p. 1101,1103;engl.Ausg.S.1059,1061
反应条件
1.) THF, hexane, - 78 deg C, 10 min, 2.) from -78 deg C to RT, 140 min,; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 53, # 20 p. 4736 - 4745
参考文献
Chemische Berichte, , vol. 60, p. 1868
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 59, p. 1138
参考文献
Chemische Berichte, , vol. 60, p. 1872
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 59, p. 1145
