2,4-二甲基-3-戊酮合成路线 （共 349 条）
反应条件
1.1: n-butyllithium / hexane; pentane / -40 °C
1.2: -40 - 20 °C
2.1: tetrahydrofuran; diethyl ether; perdeuterocyclohexane / 60 °C
View Scheme
参考文献
Knorr; Boehrer; Schubert
Chemistry - A European Journal, 2012 , vol. 18, # 24 p. 7506 - 7515
反应条件
1: (reductive amination)
2: BCl3, Et3N / toluene
View Scheme
参考文献
Turner,H.S.; Warne,R.J.
Journal of the Chemical Society, 1965 , p. 6421 - 6450
反应条件
4,4'-di-tert-butylbiphenyl; lithium in tetrahydrofuran
T=-80 - -50°C; 2.75 h;
参考文献
Yus, Miguel; MacIa, Beatriz; Gomez, Cecilia; Soler, Tatiana; Falvello, Larry R.; Fanwick, Phillip E.
Tetrahedron, 2005 , vol. 61, # 15 p. 3865 - 3871
反应条件
4,4'-di-tert-butylbiphenyl; lithium in tetrahydrofuran
T=-80 - -50°C; 2.75 h;
参考文献
Yus, Miguel; MacIa, Beatriz; Gomez, Cecilia; Soler, Tatiana; Falvello, Larry R.; Fanwick, Phillip E.
Tetrahedron, 2005 , vol. 61, # 15 p. 3865 - 3871
参考文献
Gupta,R.P. et al.
Tetrahedron, 1976 , vol. 32, p. 1917 - 1920
反应条件
ethanol; hydrazine hydrate
参考文献
Giese, Bernd; Erfort, Ulrich
Angewandte Chemie, 1982 , vol. 94, # 2 p. 133
反应条件
2: durch Behandlung des erhaltenen Kohlenwasserstoffgemisches C12H24 mit Wasserstoff und Nickel bei 200-250grad
View Scheme
参考文献
Murat; Amouroux
Bulletin de la Societe Chimique de France, 1914 , vol. <4>15, p. 160
Chem. Zentralbl., 1914 , vol. 85, # I p. 958
反应条件
sodium amide in N,N,N',N',N'',N''-hexamethylphosphoric triamide; toluene
12 h; Ambient temperature;
参考文献
Hopf, Henning; Lipka, Helmut
Chemische Berichte, 1991 , vol. 124, # 9 p. 2075 - 2084
反应条件
potassium hydroxide; diethyl ether
参考文献
Petrow et al.
Doklady Akademii Nauk SSSR, 1953 , vol. 91, p. 857,859
Chem.Abstr., 1954 , p. 10575
参考文献
Jozitsch
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1906 , vol. 38, p. 658
