苯基(2-甲基-1-丙烯基)甲酮合成路线 （共 92 条）
反应条件
1.1: t-BuOK; BuLi / hexane; tetrahydrofuran / 2 h / -95 °C
1.2: ClSnBu3 / hexane; tetrahydrofuran / 2 h / -95 - -50 °C
1.3: 0.11 g / LiCl; CuCl / Pd(PPh3)4 / dimethylsulfoxide / 2 h / 25 °C
2.1: 86 percent / Amberlyst-15 / CH2Cl2 / 1 h / 25 °C
View Scheme
参考文献
Tivola, Paolo Balma; Deagostino, Anna; Prandi, Cristina; Venturello, Paolo
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 4 p. 437 - 441
反应条件
1.1: t-BuOK; BuLi / hexane; tetrahydrofuran / 2 h / -95 °C
1.2: ClSnBu3 / hexane; tetrahydrofuran / 2 h / -95 - -50 °C
1.3: 0.11 g / LiCl; CuCl / Pd(PPh3)4 / dimethylsulfoxide / 2 h / 25 °C
2.1: 86 percent / Amberlyst-15 / CH2Cl2 / 1 h / 25 °C
View Scheme
参考文献
Tivola, Paolo Balma; Deagostino, Anna; Prandi, Cristina; Venturello, Paolo
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 4 p. 437 - 441
反应条件
1.1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 0.25 h / 0 °C / Inert atmosphere
1.2: 6 h / Inert atmosphere
2.1: tris-(dibenzylideneacetone)dipalladium(0); tris(4-methylphenyl)-phosphine / toluene / 12 h / 150 °C / Inert atmosphere
View Scheme
参考文献
Rodriguez, Nuria; Manjolinho, Filipe; Gruenberg, Matthias F.; Goossen, Lukas J.
Chemistry - A European Journal, 2011 , vol. 17, # 49 p. 13688 - 13691
反应条件
1: tetrahydrofuran / 2 h / 0 - 20 °C / |Inert atmosphere
2: manganese(IV) oxide / dichloromethane / 20 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Harris, Michael R.; Konev, Mikhail O.; Jarvo, Elizabeth R.
Journal of the American Chemical Society, 2014 , vol. 136, # 22 p. 7825 - 7828
反应条件
1: tetrahydrofuran / 2 h / 0 - 20 °C / |Inert atmosphere
2: manganese(IV) oxide / dichloromethane / 20 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Harris, Michael R.; Konev, Mikhail O.; Jarvo, Elizabeth R.
Journal of the American Chemical Society, 2014 , vol. 136, # 22 p. 7825 - 7828
参考文献
Smith; Kelly
Journal of the American Chemical Society, 1952 , vol. 74, p. 3305,3308
反应条件
aluminium trichloride
参考文献
Taylor
Journal of the Chemical Society, 1958 , p. 3922
Full Text Show Details
Matsumoto et al.
Journal of Organic Chemistry, 1958 , vol. 23, p. 106
反应条件
cerium(III) chloride; acetic acid
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Bartoli, Giuseppe; Marcantoni, Enrico; Petrini, Marino; Sambri, Letizia
Chemistry--A European Journal, 1996 , vol. 2, # 8 p. 913 - 918
反应条件
Rh(cod)2SbF6 in dichloromethane
Inert atmosphere;
参考文献
Shibata, Yu; Noguchi, Keiichi; Tanaka, Ken
Journal of the American Chemical Society, 2010 , vol. 132, # 23 p. 7896 - 7898
反应条件
cerium(III) chloride; acetic acid
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Bartoli, Giuseppe; Marcantoni, Enrico; Petrini, Marino; Sambri, Letizia
Chemistry--A European Journal, 1996 , vol. 2, # 8 p. 913 - 918
