2-溴-4-异丙氧基-5-甲氧基苯甲醛合成路线 （共 2 条）
反应条件
bromine in methanol
T=0 - 20°C;
参考文献
Dion, Isabelle; Vincent-Rocan, Jean-Francois; Zhang, Lei; Cebrowski, Pamela H.; Lebrun, Marie-Eve; Pfeiffer, Jennifer Y.; Bedard, Anne-Catherine; Beauchemin, Andre M.
Journal of Organic Chemistry, 2013 , vol. 78, # 24 p. 12735 - 12749
反应条件
1: Pd2(PPh3)2Cl2; copper(l) iodide; triethylamine / 24 h / 20 °C
2: acetic acid / 4 h / 100 °C
3: tin(ll) chloride / ethyl acetate / 10 h / 20 °C
4: hydrogen / ethyl acetate / 5 h / 760.05 Torr
5: sodium cyanoborohydride / methanol / 1 h / 20 °C / pH Ca. 3
6: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran; N,N-dimethyl-formamide / 2 h / |Reflux
7: water / benzene / 120 °C
8: zinc; acetic acid / water / 5 h / 20 °C
9: boron trichloride / dichloromethane / -10 - 20 °C
View Scheme
参考文献
Dion, Isabelle; Vincent-Rocan, Jean-Francois; Zhang, Lei; Cebrowski, Pamela H.; Lebrun, Marie-Eve; Pfeiffer, Jennifer Y.; Bedard, Anne-Catherine; Beauchemin, Andre M.
Journal of Organic Chemistry, 2013 , vol. 78, # 24 p. 12735 - 12749
